Religious bondage shackles and debilitates the mind and unfits it for every noble enterprise…. During almost fifteen centuries has the legal establishment of Christianity been on trial. What have been its fruits? More or less, in all places, pride and indolence in the clergy; ignorance and servility in laity; in both, superstition, bigotry, and persecution (James Madison, A Memorial and Remonstrance, on the Religious Rights of Man: Written in 1784-85)